바로가기  >

Abstract
A propylene cross-bridged macrocyclic chelator with two phosphonate pendant arms (PCB-TE2P) was synthesized from cyclam. Various properties of the synthesized chelator, including Cu-complexation, Cu-complex stability, 64Cu-radiolabeling, and in vivo behavior, were studied and compared with those of a previously reported propylene cross-bridged chelator (PCB-TE2A).

Author information
Nikunj Bhatt, Nisarg Soni, Yeong Su Ha, Woonghee Lee, Darpan N. Pandya, Swarbhanu Sarkar, Jung Young Kim, Hochun Lee, Sun Hee Kim, Gwang Il An, and Jeongsoo Yoo​

1Department of Molecular Medicine, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University , Daegu 700-422, South Korea.
2Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences , Seoul 139-706, South Korea.
3Department of Energy Systems Engineering, Daegu Gyeongbuk Institute of Science & Technology , Daegu 711-873, South Korea.
4Western Seoul Center, Korea Basic Science Institute , Seoul 120-140, Korea.