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  • [Med Phys .] Flexible real-time skin dosimeter based on a thin-film copper indium gallium selenide solar cell for electron radiation therapy
    전자선 방사선치료 검증을 위한 박막 구리 인듐 갈륨 셀렌화물 태양 전지 기반 플렉서블 실시간 피부 선량계 개발

    국립암센터, 서울대병원 / 신동석, 신동호*, 손재만*

  • 출처
    Med Phys .
  • 등재일
    2023 Apr
  • 저널이슈번호
    50(4):2402-2416.
  • 내용

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    Abstract
    Purpose: Various dosimeters have been proposed for skin dosimetry in electron radiotherapy. However, one main drawback of these skin dosimeters is their lack of flexibility, which could make accurate dose measurements challenging due to air gaps between a curved patient surface and dosimeter. Therefore, the purpose of this study is to suggest a novel flexible skin dosimeter based on a thin-film copper indium gallium selenide (CIGS) solar cell, and to evaluate its dosimetric characteristics.

    Methods: The CIGS solar cell dosimeter consisted of (a) a customized thin-film CIGS solar cell and (b) a data acquisition (DAQ) system. The CIGS solar cell with a thickness of 0.33 mm was customized to a size of 10 × 10 mm2 . This customized solar cell plays a role in converting therapeutic electron radiation into electrical signals. The DAQ system was composed of a voltage amplifier with a gain of 1000, a voltage input module, a DAQ chassis, and an in-house software. This system converted the electrical analog signals (from solar cell) to digital signals with a sampling rate of ≤50 kHz and then quantified/visualized the digital signals in real time. We quantified the linearity/ sampling rate effect/dose rate dependence/energy dependence/field size output factor/reproducibility/curvature/bending recoverability/angular dependence of the CIGS solar cell dosimeter in therapeutic electron beams. To evaluate clinical feasibility, we measured the skin point doses by attaching the CIGS solar cell to an anthropomorphic phantom surface (for forehead, mouth, and thorax). The CIGS-measured doses were compared with calculated doses (by treatment planning system) and measured doses (by optically stimulated luminescent dosimeter).

    Results: The normalized signals of the solar cell dosimeter increased linearly as the delivered dose increased. The gradient of the linearly fitted line was 1.00 with an R-square of 0.9999. The sampling rates (2, 10, and 50 kHz) of the solar cell dosimeter showed good performance even at low doses (<50 cGy). The solar cell dosimeter exhibited dose rate independence within 1% and energy independence within 3% error margins. The signals of the solar cell dosimeter were similar (<1%) when penetrating the same side of the CIGS cell regardless of the rotation angle of the solar cell. The field size output factor measured by the solar cell dosimeter was comparable to that measured by the ion chamber. The solar cell signals were similar between the baseline (week 1) and the last time point (week 4). Our detector showed curvature independence within 1.8% (curvatures of <0.10 mm- ) and bending recovery (curvature of 0.10 mm-1 ). The differences between measured doses (CIGS solar cell dosimeter vs. optically stimulated luminescent dosimeter) were 7.1%, 9.6%, and 1.0% for forehead, mouth, and thorax, respectively.

    Conclusion: We present the construction of a flexible skin dosimeter based on a CIGS solar cell. Our findings demonstrate that the CIGS solar cell has a potential to be a novel flexible skin dosimeter for electron radiotherapy. Moreover, this dosimeter is manufactured with low cost and can be easily customized to various size/shape, which represents advantages over other dosimeters.

     

     

    Affiliations

    Dong-Seok Shin 1, Tae-Ho Kim 1, Jeong-Eun Rah 2, Se Byeong Lee 1, Young Kyung Lim 1, Jonghwi Jeong 1, Haksoo Kim 1, Dongho Shin 1, Jaeman Son 3
    1Proton Therapy Center, National Cancer Center, Goyang, Republic of Korea.
    2Department of Radiation Oncology, Myongji Hospital, Goyang, Republic of Korea.
    3Department of Radiation Oncology, Seoul National University Hospital, Seoul, Republic of Korea.

  • 키워드
    copper indium gallium selenide solar cell; electron radiotherapy; flexible dosimeter; skin dosimeter.
  • 편집위원

    새로운 타입의 전자선용 필름형의 플랙시블한 검출기에 대한 연구로서 피부선량 측정에 유용하게 사용될 수 있음

    2023-06-09 09:16:17

  • 편집위원2

    본 논문은 얇고 유연한 성질의 태양전지를 방사선 센서로 사용하여, 방사선치료 환자의 피부 선량측정에 응용하기 위한 예비 연구이다. 방사선치료시 투여되는 선량을 모니터링하는 것은 환자 관리에 중요하지만, 환자 심부에 선량계를 삽입하지 못하기 때문에 피부 선량 측정으로 투여되는 선량을 추정하는 방법이 적용되고 있다. 특히 전자선의 경우에 표재성 치료에 적용되므로 피부선량의 측정만으로 비교적 정확하게 치료 부위의 선량을 추정할 수 있다. 그렇지만 피부 표면은 대부분 굴곡이 있고 평탄하지 않기 때문에 열형광선량계나 유리선량계와 같이 작은 소자를 부착하여 측정하는 방법이 적용되고 있으나 이들 선량계는 모두 판독과정이 필요하여 실시간 측정이 불가능하다. 또한 소자의 두께로 인하여 투여 선량에 영향을 줄 수도 있다. 본 논문에서는 유연하고 얇은 박막 태양전지(CIGS solar cell)를 이용하여 실시간 선량측정이 가능하도록 한 것을 특징으로 하고 있다. 검출기(태양전지) 신호 획득에 50 kHz DAQ 모듈을 사용하였고, 선량계에 대한 선량, 선량률, 에너지 의존성, 방향 의존성 등 주요 물리적 특성을 평가하는 과정과 결과가 제시되어 있다.

    2023-06-09 09:19:04

  • 편집위원3

    지금까지 피부선량을 측정할 수 있는 선량계는 몇 개 되지 않는데, 나름대로 장점과 단점들이 있어서 전천후로 사용하기에는 용이하지 않는데, 새로운 타입으로 플렉서블하면서도 효율이 좋은 선량계를 만들 수 있는 가능성이 좋은 타입으로 생각된다.

    2023-06-09 09:20:00

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