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  • [Med Phys.] Determining the energy spectrum of clinical linear accelerator using an optimized photon beam transmission protocol.

    연세대 / 최현준, 민철희*

  • 출처
    Med Phys.
  • 등재일
    2019 Jul
  • 저널이슈번호
    46(7):3285-3297. doi: 10.1002/mp.13569. Epub 2019 Jun 1.
  • 내용

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    Abstract
    PURPOSE:
    The complex beam delivery techniques for patient treatment using a clinical linear accelerator (linac) may result in variations in the photon spectra, which can lead to dosimetric differences in patients that cannot be accounted for by current treatment planning systems (TPSs). Therefore, precise knowledge of the fluence and energy spectrum (ES) of the therapeutic beam is very important. However, owing to the high energy and flux of the beam, the ES cannot be measured directly, and validation of the spectrum modeled in the TPS is difficult. The aim of this study is to develop an efficient beam transmission measurement procedure for accurately reconstructing the ES of a therapeutic x-ray beam generated by a clinical linac.

    METHODS:
    The attenuation of a 6 MV photon beam from an Elekta Synergy Platform clinical linac through different thicknesses of graphite and lead was measured using an ion chamber. The response of the ion chamber as a function of photon energy was obtained using the Monte Carlo (MC) method in the Geant4 simulation code. Using the curves obtained in the photon beam transmission measurements and the ion chamber energy response, the ES was reconstructed using an iterative algorithm based on a mathematical model of the spectrum. To evaluate the accuracy of the spectrum reconstruction method, the reconstructed ES (ESrecon ) was compared to that determined by the MC simulation (ESMC ).

    RESULTS:
    The ion chamber model in the Geant4 simulation was well validated by comparing the ion chamber perturbation factors determined by the TRS-398 calibration protocol and EGSnrc; the differences were within 0.57%. The number of transmission measurements was optimized to 10 for efficient spectrum reconstruction according to the rate of increase in the spectrum reconstruction accuracy. The distribution of ESrecon obtained using the measured transmission curves was clearly similar to the reference, ESMC , and the dose distributions in water calculated using ESrecon and ESMC were similar within a 2% local difference. However, in a heterogeneous medium, the dose discrepancy between them was >5% when a complex beam delivery technique composed of 171 control points was used.

    CONCLUSIONS:
    The proposed measurement procedure required a total time of approximately 1 h to obtain and analyze 20 transmission measurements. In addition, it was confirmed that the transmission curve of high-Z materials influences the accuracy of spectrum reconstruction more than that of low-Z materials. A well-designed transmission measurement protocol suitable for clinical environments could be an essential tool for better dosimetric accuracy in patient treatment and for periodic verification of the beam quality.

     


    Author information

    Choi HJ1, Park H1, Yi CY2, Kim BC2, Shin WG1, Min CH1.
    1
    Department of Radiation Convergence Engineering, Yonsei University, 1 Yeonsedae-gil, Heungeop-myeon, Wonju, 26493, Korea.
    2
    Center for Ionizing Radiation, Korea Research Institute of Standards and Science, Daejeon 34113, Korea.

  • 키워드
    Geant4; energy spectrum reconstruction; ion chamber; linear accelerator; transmission measurement
  • 편집위원

    - 방사선치료에서 입자선인 전자선의 경우에는 깊이에 따라 에너지가 달라지지만 x선은 깊이에 따라 에너지가 그리 크게 변하지 않고 변한다 하더라도 방사선 에너지가 인체에 미치는 영향이 다르지 않기 때문에 에너지에 대한 고려는 하지 않고 있다. 그러나 논문에 의하면 에너지의 변화를 고려한다면 선량차이를 보다 정확하게 알 수 있고, 특히 컨트롤포인트가 많은 복잡한 치료에서 그 차이가 크다고 하니 앞으로 좀 더 면밀히 볼 필요가 있겠다

    2019-08-30 10:05:19

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