글로벌 연구동향
방사선종양학
- 2021년 10월호
[Br J Radiol.] CT findings of acute radiation-induced pneumonitis in breast cancer이화의대 / 정원근, 김규보*
- 출처
- Br J Radiol.
- 등재일
- 2021 Aug 1
- 저널이슈번호
- 94(1124):20200997. doi: 10.1259/bjr.20200997. Epub 2021 Jun 16.
- 내용
Abstract
Objectives: To evaluate the CT findings of acute radiation pneumonitis (RP) in breast cancer patients undergoing post-operative radiotherapy, and to analyze clinicodosimetric factors associated with acute RP.Methods: Between 2015 and 2017, 61 patients with breast cancer who underwent follow-up chest CT at 3 months after radiotherapy were analyzed. The degree of acute RP on CT was evaluated by the change of extent and scoring system (grade 0, no RP; Grade 1, ground-glass opacities (GGOs); Grade 2, GGOs and/or consolidations; Grade 3, clear focal consolidation; Grade 4, dense consolidation). The dosimetric parameters were calculated from the dose-volume histogram of RT.
Results: The acute RP on CT was scored as follows: Grade 0, in 37.7%, Grade 1 in 13.1%, Grade 2 in 44.3%, and Grade 3 in 4.9%. The median extent of RP in patients with Grades 1 to 3 was 6.2 ml (range, 0.2-95.9). There were no clinicodosimetric factors significantly associated with the presence of RP or its severity. One patient developed symptomatic RP.
Conclusion: This study showed no correlation between acute RP and clinicodosimetric factors, and acute RP based on CT findings were much more common than symptomatic RP.
Advances in knowledge: CT findings of acute RP or extent of RP were not significantly related to clinicodosimetric factors in breast cancer patients.
Affiliations
Wonguen Jung 1 , Sung Shine Shim 2 , Kyubo Kim 1
1 Department of Radiation Oncology, Ewha Womans University College of Medicine, Seoul, South Korea.
2 Department of Radiology, Ewha Womans University College of Medicine, Seoul, South Korea.
- 덧글달기
- 이전글 [Breast Cancer Res Treat.] Dynamics of circulating tumor DNA during postoperative radiotherapy in patients with residual triple-negative breast cancer following neoadjuvant chemotherapy: a prospective observational study.
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