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No abstract

This study aimed to elucidate the treatment outcomes and the patterns of failure of SDC treated with surgery and PORT, among patients enrolled in the multi-institutional retrospective study of the Korean Radiation Oncology Group (KROG) 13-09.

In summary, the present study demonstrated that surgery followed by PORT was effective in LRC, but not in DC, in major salivary gland SDC. Optimization of radical surgery, proper RT field design based on this study’s results, and application of novel systemic agents to minimize DM would be indispensable for future SDC treatment.

Affiliations

Dong Soo Lee  1 , Chang Geol Lee  2 , Ki Chang Keum  2 , Seung Yeun Chung  2 , Taehyung Kim  2 , Hong-Gyun Wu  3   4   5 , Jin Ho Kim  3 , Myung-Whun Sung  6 , Soon-Hyun Ahn  6 , Kwan Ho Cho  7 , Ki Mun Kang  8 , Young-Taek Oh  9 , Jin Hee Kim  10 , Min Kyu Kang  11
1 Department of Radiation Oncology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
2 Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, South Korea.
3 Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, South Korea.
4 Cancer Research Institution, Seoul National University College of Medicine, Seoul, South Korea.
5 Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul, South Korea.
6 Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, South Korea.
7 Proton Therapy Center, Research Institute and Hospital, National Cancer Center, Goyang, South Korea.
8 Department of Radiation Oncology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Jinju, South Korea.
9 Department of Radiation Oncology, Ajou University School of Medicine, Suwon, South Korea.
10 Department of Radiation Oncology, Keimyung University, School of Medicine, Daegu, South Korea.
11 Department of Radiation Oncology, School of Medicine, Kyungpook National University, Daegu, South Korea.